Numerous conditions and diseases can result in damage to the kidneys. The most common causes of and main risk factors for kidney disease are diabetes and hypertension.
Features of 3 in 1 Renal Function Test Strip
Intended use
The 3 in 1 Renal Function Test Strip work with the Renal Function Analysis Meter(RFM-101)or Dry Biochemical(DBM-101). Analysis Meter to measure the Uric Acid (UA), Creatinine (CR/CREA) and Urea (UR/UREA) concentration in whole blood, plasma and serum. For professional use.
The 3 in 1 Renal Function Test Strip are used in the diagnosis various kidney diseases such as nephritis Renal function tests (RFM-101) are a group of tests that may be performed together to evaluate kidney (renal) function. The tests measure the concentrations of Uric Acid (UA),Creatinine (CR) and Urea (UR).in the blood to determine the current health of the kidneys.
If the kidneys are not functioning properly, waste products can accumulate in the blood and fluid levels can increase to dangerous volumes, causing damage to the body or a potentially life-threatening situation. Numerous conditions and diseases can result in damage to the kidneys. The most common causes of and main risk factors for kidney disease are diabetes and hypertension.
Principle and reference values
The 3 in 1 Renal Function Test Strip use a timed-endpoint method to measure the Uric Acid (UA),Creatinine(CR) and Urea (UR) concentrations in whole blood, serum or plasma. The system monitors the change in absorbance at 620 nm at a fixed-time interval. The change in absorbance is directly proportional to the concentration of metabolite in the specimen.
UA: In the reaction, the uric acid is oxidized to allantoin and hydrogen peroxide by uricase.
Peroxidase catalyzes the reaction of hydrogen peroxide with 4-aminoantipyrine and phenol to produce a colored quinoneimine product. The change in absorbance is directly proportional to the concentration of uric acid in the specimen.
CR: Creatinine in the specimen are hydrolyzed to creatine by the action of creatininase. A sequence of three coupled enzymatic steps using creatinase, sarcosine oxidase, and peroxidase causes the oxidative coupling of 4-aminoantipyrine to form a blue dye.
UR: Urea in the specimen are hydrolyzed to NH 3 and CO 2 by the action of urease,and an indicator layer containing an indicator which produces a detectable change by gaseous ammonia.
Tests Desirable
-Uric Acid (UA)
Men: 0.202~0.416mmol/L(3.40~6.99mg/dL)
Women:0.142~0.340mmol/L(2.39~5.72mg/dL)
-Creatinine (CR)
Men: 0.070~0.115mmol/L(0.79~1.30mg/dL)
Women:0.044~0.080mmol/L(0.50~0.90mg/dL)
-Urea (UR)
1.70~8.30mmol/L(10.21~49.85mg/dL)
Reference ranges may vary between laboratories. Every laboratory should establish its own reference range as needed.
UA, CR, UR levels will have big physiological fluctuations depending on food consumed or exercise.
3 in 1 Renal function test strip
Test strip appears as shown below:
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